Speeding up the research and development of drying equipment in China's pharmaceutical industry is the top priority

- May 07, 2019 -

Although the development and quality of pharmaceutical drying equipment have been improved in recent years, on the whole, the drying of traditional Chinese medicines is basically in the state of borrowing other materials drying equipment, with few special equipment and no serialization and standardization; less systematic research, accelerating the research and development of drying equipment in the pharmaceutical industry is the most important thing!

< P> At present, for dried Chinese medicines and drinks. The water content of tablets is usually 8%~12%. In my opinion, this standard is too general and does not take into account the differences between traditional Chinese medicines and decoction pieces. As we all know, the types of chemical constituents, the types of microorganisms, the medicinal parts and the structure of tissues in different pieces of decoction may be different, so their effectiveness, safety and stability are affected by water to varying degrees. If a unified standard is used, it seems biased. This requires researchers to study the correlation among water, chemical composition and curative effect, reveal and predict the influence of drying degree on all aspects of Chinese herbal medicines, and formulate reasonable and standard water content standards for Chinese herbal medicines, so as to improve the quality of Chinese herbal medicines. The drying process of

Chinese herbal medicines and decoction pieces is actually a dynamic change process of water, heat and active ingredients, which interact and restrict each other, and then reach a relative equilibrium state. In the study, we should not only investigate the factors that influence the three factors in the drying process, such as drying temperature, time, space scale, environmental temperature, humidity, air velocity and surface morphology, but also investigate the dynamic change process and mutual restriction relationship of the three factors under the influence of these factors. We should also design and develop computer software to simulate different factors with the help of a large number of experimental data. Based on the comprehensive effect of Zi, a drying model of Chinese herbal medicines was established. Through the establishment and prediction of the model, various influencing factors are adjusted to find the optimal combination, so that the water, heat and effective ingredients can achieve the best balance state and drying effect. At present, the research on drying technology is mostly limited to the comparison of working methods, drying time and energy consumption. There are few reports on the comprehensive study of mass and heat transfer mechanism, effective ingredient change mechanism, drying process parameters optimization and drying equipment design, which means that there are few perfect drying technology research on traditional Chinese medicine varieties.

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