Application of Powder Drying in Pharmaceutical Field

- May 07, 2019 -

Henan Microwave Equipment Network News: For the drying of special products such as powder, its application focuses on the food and medical industry. In the pharmaceutical industry, the application of drying equipment has been a long time. From twentieth Century to 70s, the drying room or hot air drying room was used in large quantities in the 60 and 70s. To 80s, vacuum drying equipment, and then to the boiling bed and spray drying, coating, granulating equipment were widely used. Especially in the late twentieth Century, vacuum freeze dryer and microwave dryer were also produced in China. It basically meets the requirements of the industry, especially the GMP certification of the pharmaceutical industry at the beginning of the 21st century, and promotes the development of medical equipment.

A qualified drying equipment should not only meet the needs of drying operation, but also meet the requirements of GMP. It should not only meet the requirements of strength, accuracy, surface roughness and reliability of the equipment, but also consider the structure of the equipment to be detachable, easy to clean and no dead corner, avoid dirt infiltration, remove the parts that are difficult to clean and inspect in design, adopt reliable seals, and manufacture is set up. The interior of the spare wall is smooth, and all corners should be smooth transition.

Microwave drying has the characteristics of penetrating non-metals, being reflected by metals, being absorbed by water or water-containing substances. Microwave energy radiates directly into the material layer, which raises the temperature inside the material layer, transfers the production pressure, evaporates the surface of moisture and is carried away by hot gas. The drying time is shortened by 2/3 and has disinfection effect. Microwave drying is mainly used in traditional Chinese medicine drying. It is especially conducive to the drying of water-containing materials. It has fast drying speed, high energy utilization rate, good drying and sterilization effect, high quality, continuous, automatic production, high working efficiency, good production environment, and meets the requirements of GMP. It is worth popularizing and applying. However, microwave drying technology is not suitable for drying heat-sensitive materials. In addition, whether microwave drying technology will affect the stability and efficacy of drugs should be further studied and discussed.

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